A Study on Serum Zinc Concentration in some Methamphetamine Abusers

Methamphetamine 남용자에 있어서 혈청 아연농도에 관한 연구

  • Moon, Hyung-Il (Department of Preventive Medicine and Public health, college of Medicine, Pusan National University) ;
  • Lee, Hoo-Rak (Department of Preventive Medicine and Public health, college of Medicine, Pusan National University) ;
  • Lee, Soo-Il (Department of Preventive Medicine and Public health, college of Medicine, Pusan National University)
  • 문형일 (부산대학교 의과대학 예방의학교실) ;
  • 이후락 (부산대학교 의과대학 예방의학교실) ;
  • 이수일 (부산대학교 의과대학 예방의학교실)
  • Published : 1992.06.01

Abstract

The author investigated the zinc concentrations in sera of 110 methamphetaimine abusers (male 87, female 23) and of 41 healthy official workers(male 29, female 12) using inductively coupled plasma emission spectrometer. The serum zinc concentrations were analysed according to hepatitis C virus antibody(Anti HCV), hepatitis B surface antigen(HBsAg) and alanine aminotransferase(ALT) value in both groups. The analytical results were obtained as follows 1. The mean zinc concentration of MAP abuser group($298.5{\pm]246.9{\mu}g/100ml$) was 2.5 times higher than that of control group($118.8{\pm}25.4{\mu}g/100ml$). 2. The distributions of zinc concentration in both groups were skewed pattern. 3. The zinc concentrations were higher in Anti HCV-positive group and abnormal ALT value group than Anti HCV-negative group and normal ALT value group. But HBs-Ag positive group had lower zinc concentration than HBs-Ag negative group. 4. The number of anti HCV-positive subjects was increased and the zinc concentrations were decreasd in proportion to the abusing duration of MAP.

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