An immunohistochemical study of the endocrine cells on the gastro-entero-pancreatic system of the African clawed toad, Xenopus laevis

아프리카발톱두꺼비(Xenopus laevis)의 위장췌내분비세포의 면역조직화학적 연구

The GEP endocrine cells of the African clawed toad, Xenopus laevis, were studied immunohistochemically. Five kinds of the endocrine cells were identified in this study A moderated number of 5-HT-immunoreactive cells were detected throughout the gastro intestinal tract, being almost uniform frequency. Gas/CCK -immunoreactive cells were restricted to the basal portion of the pyloric gland and among the duodenal mucosa. A rare glucagon-immunoreactive cells were weakly reacted in the fundic region of the stomach and observed in the exocrine portions of the pancreas. Somatostatine-immunoreactive cells were distributed throughout the gastrointestinal tract with except for the rectum, and not only the periphery of the islets but also the exocrine portions in the pancreas. No CGs- and insulin-immunoreactive cells were found in the gastrointestinal tract, whereas in the pancreas, the later was seen in the central region of the islets and the exocrine portions.

아프리카발톱두꺼비(Xenopus laevis)의 위장췌내분비세포를 면역조직화학적으로 관찰하였던 바 5-HT면역반응세포들은 중등도로 전장관에 고루 분포하였다. Gas/CCK면역반응세포는 유문부 장선의 기저부와 십이지장 점막상피에서 출현하였다. 소수의 glucagon면역반응세포는 위저부에서 약하게 반응하였고, 췌장에서는 외분비부에서만 관찰되었다. 직장을 제외한 전장관과 췌도 주변부 및 외분비부에서 somatostatin면역반응세포가 관찰되었다. CGs와 insulin면역반응세포는 전장관에서 관찰할 수 없었다. 그러나 insulin세포는 췌도의 중앙부와 외분비부에서 단독으로 출현하였다.