Asian-Australasian Journal of Animal Sciences

  • 제5권1호
  • /
  • Pages.29-32
  • /
  • 1992
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  • 1011-2367(pISSN)
  • /
  • 1976-5517(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
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THE EFFECTS OF PROSTAGLANDINS AND INDOMETHACIN ON OVULATION IN THE PERFUSED FOWL OVARY

  • Tanaka, K. (Laboratory of Animal Breeding, Faculty of Agriculture, Kyushu University) ;
  • Higuchi, T. (Faculty of Agriculture, Kyushu University) ;
  • Tawarazumita, M. (Faculty of Agriculture, Kyushu University) ;
  • Hertelendy, F. (Department of Obstetrics and Gynecology, St. Louis University School of Medicine)
  • 투고 : 1990.11.08
  • 심사 : 1991.11.25
  • 발행 : 1992.03.01
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초록

The effects of prostaglandins (PG) and indomethacin, a PG synthesis inhibitor, on ovulation in the perfused fowl ovary were studied. Laying hens were killed by cutting the jugular vein 18-19 h before expected ovulation of the second follicle of a clutch sequence. The cannulated ovary was dissected free and connected with a recycling perfusion apparatus. Agents to be studied for their effects on ovulation were added to the perfusion fluid. $PGF_{2{\alpha}}$ at 0.1 and 1 mg/l induced ovulation, with a success rate of 25% and 30%, respectively. The same doses of $PGE_2$ were effective at 60% and 63%, respectively. Indomethacin partially blocked gonadotrophin-induced ovulation. It is suggested that PGs may play a supportive role in the process of follicular rupture in the domestic fowl.

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연구 과제 주관 기관 : Ministry of Education, Science and Culture