시상 증후군에 동반된 대뇌 피질 혈류 변화에 대한 $^{99m}Tc-HMPAO$ Brain SPECT

Thalamic Syndrome with Related Cortical Hypoperfusion on $^{99m}Tc-HMPAO$ Brain SPECT

  • 김은경 (연세대학교 의과대학 진단방사선과학교실) ;
  • 정태섭 (연세대학교 의과대학 진단방사선과학교실) ;
  • 서정호 (연세대학교 의과대학 진단방사선과학교실) ;
  • 김동익 (연세대학교 의과대학 진단방사선과학교실) ;
  • 이종두 (연세대학교 의과대학 진단방사선과학교실) ;
  • 박창윤 (연세대학교 의과대학 진단방사선과학교실) ;
  • 홍용국 (연세대학교 의과대학 진단방사선과학교실) ;
  • 이명식 (연세대학교 의과대학 신경과학교실)
  • Kim, Eun-Kyung (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Chung, Tae-Sub (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Suh, Jung-Ho (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Kim, Dong-Ik (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Lee, Jong-Doo (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Park, Chang-Yoon (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Hong, Yong-Kook (Department of Diagnostic Radiology, College of Medicine, Yonsei University) ;
  • Lee, Myung-Sik (Department of Neurology, College of Medicine, Yonsei University)
  • 발행 : 1992.05.31

초록

Spontaneous pain and painful overreaction to external stimuli resulting from lesion confined central nervous system (CNS) were named as thalamic syndrome. Thalamic lesion and decreased regional cortical perfusion thought to the pathogenesis of thalamic syndrome due to decreased function of thalamocortical tract. We performed $^{99m}Tc-HMPAO$ regional cerebral perfusion in 10 patients with clinical diagnosis of thalamic syndrome due to thalamic lesion or near the thalamic lesion at Yonsei University Hospital, from January 1989 to August 1991. In contrast to five patients with lesions near the thalamus who did not show secondarily decreased perfusion at cerebral cortex, four among the five patients with thalamic lesions revealed decreased cortical perfusion in the ipsilateral cerebral cortex on brain SPECT. These phenomena may suggest the loss of afferent activating stimuli from the thalamus led to decreased neuronal activity and the followitng hypoperfusion of cerebral cortex, and might be one of the indirect signs for suggesting presence of the thalamocortical tract. A causal relationship between cortical hypoperfusion and neuropsychological deficit is strongly suggested.

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