Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Efficient Synthesis of An Epoxy Alcohol, A key Intermediate for$LTA_4$ Synthesis

  • Hokoon Park (Organic Chemistry Laboratory I, Korea Institute of Science & Technology) ;
  • Yong Sup Lee (Organic Chemistry Laboratory I, Korea Institute of Science & Technology) ;
  • Sang Chul Shim (Department of Chemistry, Korea Advanced Institute of Science and Technology)
  • Published : 1992.10.20
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Abstract

An efficient and very short synthesis of epoxy alcohol 5, a key intermediate for leukotriene synthesis, was described. The key reaction involves the regioselective benzylidene acetal formation from methyl 5,6,7-trihydroxyheptanoate 1.

Keywords

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Cited by

  1. ChemInform Abstract: Efficient Synthesis of an Epoxy Alcohol, a Key Intermediate for LTA4 Synthesis. vol.24, pp.16, 1992, https://doi.org/10.1002/chin.199316165