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Carbonylation of Bromo(Bromomethyl)Benzenes to Alkyl Carboalkoxyphenylacetates Catalyzed by Cobalt Carbonyl

  • Shim, Sang-Chul (Department of Industrial Chemistry, Kyungpook National University) ;
  • Doh, Chil-Hoon (Department of Industrial Chemistry, Kyungpook National University) ;
  • Lee, Dong-Yub (Department of Industrial Chemistry, Kyungpook National University) ;
  • Youn, Young-Zoo (Department of Industrial Chemistry, Kyungpook National University) ;
  • Lee, Seung-Yub (Department of Industrial Chemistry, Kyungpook National University) ;
  • Chae, Shin-Ae (Department of Industrial Chemistry, Kyungpook National University) ;
  • Oh, Dae-Hee (Department of Surface Coating Engineering, Pusan National Univerwity of Technology) ;
  • Oh, Hun-Seung (Lucky R & D Center, Science Town)
  • Published : 1992.02.20

Abstract

A synthetic method for bis-carbonylation of bromo(bromomethyl)benzenes was described. Alkyl carboalkoxyphenylacetates were easily prepared by the carbonylation of benzylic and arylic bromide moieties in bromo(bromomethyl)benzenes with alcohols in the presence of $K_2CO_3,\;CH_3I$, and a catalytic amount of cobalt carbonyl under the atmospheric pressure of carbon monoxide at room temperature in good to excellent yields. The base played a decisive role in the selectivity of product and $K_2CO_3$ was the best one among bases used.

Keywords

References

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Cited by

  1. ChemInform Abstract: Carbonylation of Bromo(bromomethyl)benzenes to Alkyl Carboalkoxyphenylacetates Catalyzed by Cobalt Carbonyl. vol.23, pp.22, 1992, https://doi.org/10.1002/chin.199222131