Archives of Pharmacal Research
- Volume 15 Issue 4
- /
- Pages.374-375
- /
- 1992
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
A Steroselective Synthesis of (22R, 23R)-Methylenecholesterol
Abstract
The marine sterol (22R, 23R)-methylenecholesterol 1 has been synthesized from readily available C-22 steroidal ester 2 utilizing an intermolecular acyclic ester enolate alkylation as the key step.
Keywords
- Synthesis;
- marine sterol.;
- (22R.23R)-methylenecholesterol;
- intermolecular acyclic ester enolate alkylation