YAKHAK HOEJI (약학회지)
- Volume 36 Issue 5
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- Pages.486-490
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Characterization of Multidrug Resistant Plasmid of Staphylococcus aureus
황색포도상구균의 항생제 다제내성을 갖는 플라스미드의 동정
- Kim, Ki-Hyun (College of Pharmacy, Kyungsung University) ;
- Lee, Dae-Woon (College of Pharmacy, Kyungsung University) ;
- Kim, Jong-Myung (College of Pharmacy, Kyungsung University) ;
- Moon, Kyung-Ho (College of Pharmacy, Kyungsung University)
- Published : 1992.10.29
Abstract
The clinical isolate Staphylococcus aureus SA2 was resistant to ampicillin, Chloramphenicol, clindamycin, erythromycin, gentamicin, kanamycin, methicillin, streptomycin, and tobramycin and harboured more than two kinds of plasmids. Transformation experiment demonstrated that 40.98-kb plasmid(pKH2) encoded resistance to ampicillin, clindamycin, erythromycin, kanamycin, and streptomycin. The cleavage map of a pKH2 was determined by restriction enzyme mapping techniques. Cleavage map is given for BamHI, BglI, BstEII, SalI and XhoI.
Keywords
- Staphylococcus aureus;
- protoplast transformation;
- ampicillin-cl indamycin-erythromycin-kanamycin-streptomycin resistant plasmid;
- restriction map