YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Analgesic Components of the Rhizoma of Astilbe chinensis var. davidii

노루오줌 근경의 진통성분

  • Oh, Kap-Jin (Central Research Institute, Samjin Pharmaceutical Co., LTD.) ;
  • Choi, Yun-Seuk (Central Research Institute, Samjin Pharmaceutical Co., LTD.) ;
  • Choi, Il-Shik (Central Research Institute, Samjin Pharmaceutical Co., LTD.) ;
  • Park, Si-Kyung (Central Research Institute, Samjin Pharmaceutical Co., LTD.) ;
  • Lee, Kyou-Heung (Central Research Institute, Samjin Pharmaceutical Co., LTD.) ;
  • Chung, Sun-Gan (Central Research Institute, Samjin Pharmaceutical Co., LTD.) ;
  • Cho, Eui-Hwan (Central Research Institute, Samjin Pharmaceutical Co., LTD.)
  • 오갑진 (삼진제약 주식회사 중앙연구소) ;
  • 최윤석 (삼진제약 주식회사 중앙연구소) ;
  • 최일식 (삼진제약 주식회사 중앙연구소) ;
  • 박시경 (삼진제약 주식회사 중앙연구소) ;
  • 이규흥 (삼진제약 주식회사 중앙연구소) ;
  • 정순간 (삼진제약 주식회사 중앙연구소) ;
  • 조의환 (삼진제약 주식회사 중앙연구소)
  • Published : 1992.10.29
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Abstract

Astilbes rhizoma has been used for headache, arthralgia, chronic bronchitis and stomachalgia in traditional chinese medicine. The analgesic activities and their components of Astilbe chinensis var. davidii Rhizomes were evaluated. The ether and ethylacetate fractions of 70% EtOH extract showed considerable analgesic activities by acetic acid induced writhing method. Compound $1{\sim}5$ were isolated from ethylacetate fraction and identified as gallic acid, (+)-catechin, (+)-gallocatechin, bergenin and 11-O-galloylbergenin on the basis of spectroscopic methods. Among them (+)-gallocatechin showed stronger analgesic activity than that of other compounds.

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