Effect of Endogenous Estrogen on Calcium Metabolism During Ovulation Induction

배란유도시 내인성 Estrogen이 칼슘대사에 미치는 영향에 관한 연구

  • Yoon, D.Y. (Department of Obstetrics and Gynecology, Yonsei University College of Medicine) ;
  • Park, K.H. (Department of Obstetrics and Gynecology, Yonsei University College of Medicine) ;
  • Lee, B.S. (Department of Obstetrics and Gynecology, Yonsei University College of Medicine) ;
  • Lee, B.Y. (Department of Obstetrics and Gynecology, Yonsei University College of Medicine) ;
  • Song, C.H. (Department of Obstetrics and Gynecology, Yonsei University College of Medicine)
  • 윤달영 (연세대학교 의과대학 산부인과학교실) ;
  • 박기현 (연세대학교 의과대학 산부인과학교실) ;
  • 이병석 (연세대학교 의과대학 산부인과학교실) ;
  • 이보연 (연세대학교 의과대학 산부인과학교실) ;
  • 송찬호 (연세대학교 의과대학 산부인과학교실)
  • Published : 1991.12.31

Abstract

The role of estrogen in calcium metabolism has not been well documented. To further investigate the effects of endogenous estrogen on the calcium regulating hormones in women, we correlated the changes of estrogen level with those of calcium regulating hormones during ovulation induction in 12 hypogonadal and 8 normally menstruating women. During ovulation induction, the serum leveles of estradiol rose from 40.0 to 831.0pg/ml. There were no significant changes in the serum leveles of total calcium, inorganic phosphorus, parathyroid hormone, calcitonin. However, 1, $25-(OH)_2D_3$ rose significantly from 31.0 to 47.2pg.ml as the endogenous $E_2$ increaed (p<0.005).

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