Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Review of Subacute Necrotizing Lymphadenitis

아급성 괴사성 임파선염에 대한 임상적 관찰

  • Jang, Chang-Hoon (Department of Internal Medicine, Catholic University Medical College) ;
  • Kwon, Soon-Seog (Department of Internal Medicine, Catholic University Medical College) ;
  • Kim, Young-Kyoon (Department of Internal Medicine, Catholic University Medical College) ;
  • Kim, Kwan-Hyoung (Department of Internal Medicine, Catholic University Medical College) ;
  • Han, Ki-Don (Department of Internal Medicine, Catholic University Medical College) ;
  • Moon, Hwa-Sik (Department of Internal Medicine, Catholic University Medical College) ;
  • Song, Jeong-Sup (Department of Internal Medicine, Catholic University Medical College) ;
  • Park, Sung-Hak (Department of Internal Medicine, Catholic University Medical College)
  • 장창훈 (가톨릭대학 의학부 내과학교실) ;
  • 권순석 (가톨릭대학 의학부 내과학교실) ;
  • 김영균 (가톨릭대학 의학부 내과학교실) ;
  • 김관형 (가톨릭대학 의학부 내과학교실) ;
  • 한기돈 (가톨릭대학 의학부 내과학교실) ;
  • 문화식 (가톨릭대학 의학부 내과학교실) ;
  • 송정섭 (가톨릭대학 의학부 내과학교실) ;
  • 박성학 (가톨릭대학 의학부 내과학교실)
  • Published : 1991.09.30
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Abstract

Subacute necrotizing lymphadenitis is characterized by cervical lymphadenpathy in young patients and mistaken for malignant disease both clinically and histologically. Microscopically, there is a varying degree of effacement of the lymph node architecture and necrosis with an infiltrate of histiocytic cells and absence of polymorphs. We have experienced 4 cases of cervical lymphadenopathy accompanied by fever. All cases had complete recovery to conservative treatment only. The excised lymph nodes were moderately enlarged and typically showed varying degree of necrotizing lesions, and abundant karyorrhectic debris, scattered fibrin deposits, aggregates of large mononuclear cells, and a paucity of plasma cell and neutrophils. For investigating the etiology and pathogenesis of this lesion, further clinical study and stepwise pathologic and immunologic planning would be valuable.

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