Difference of Toxicities among Tissues in the Pufferfish Fugu xanthopterus('Ggachibog')

까치복, Fugu xanthopterus의 조직별 독성차이

Twenty-four specimens of the pufferfish Fugu xantheptens, Korean name, 'Ggachibog', collected at a fish market of Pusan were examined for anatomical distribution of toxicity by the mouse bioassay method. Frequency of toxic specimens was 88, 75, 54, 13, 71, 80 and $71\%$, in terms of liver, intestine, skin, muscle, testis, ovary and bile, respectively. Their the highest toxicity scores were 417, 387, 112, 17, 39, 403 and 178 MU/g, respectively; and average toxicity values were $110\pm25.0(mean \pm S.E.)$, $73\pm20.3,\;17.8\pm 5.1,\;2.7\pm1.1,\;15.6\pm5.4,\;115\pm33.0\;and\;34\pm9.3 MU/g,$ respectively. A significant correlation between the toxicities of liver and intestine(r=0.93), between those of liver and skin (r=0.79) and between those of liver and ovary(r=0.83) was observed.

부산 시내 어시장에서 구입된 까치복어, Fugu xanthopterus의 조직부위별 독성과 특정부위의 독성간 상호관계를 mouse bioassay법에 의하여 비교 검토하였다. 즉, 개체당 전체 독량이 0-36,816 MU로써 개체에 따라 독성차이가 있으며, 간, 난소 그리고 내장의 평균독성은 각각 $110.0\pm25.0,\;115.0\pm33.0\;$ 및 $73.0\pm20.3\;MU/g$(평균치$\pm$표준편차)이었다 또한 각 부위별 독성의 빈도순서는 간$(88\%)$, 난소$(80\%)$ 내장$(75\%)$, 정소$(71\%)$, 담즙$(71\%)$, 껍질(54\%)$, 그리고 근육조직$(13\%)$의 순이었다. 한편 간과 내장, 껍질, 난소조직의 독성은 그 상관계수가 각각 r=0.93, r=0.79 및 r=0.83으로 뚜렷한 상관관계를 나타내었다.