Scintigraphic Evaluation of Multiple Endocrine Neoplasia Type 2 (MEN Type 2)

MEN Type 2 (Sipple's Syndrome)의 신티그램 소견

  • Lee, Jae-Tae (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, Kyu-Bo (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Whang, Kee-Suk (Department of Nuclear Medicine, School of Medicine, Kyungpook National University) ;
  • Kim, Bo-Wan (Department of Internal Medicine, School of Medicine, Kyungpook National University) ;
  • Lee, In-Kyu (Department of Internal Medicine, School of Medicine, Kyemyung University)
  • 이재태 (경북대학교 의과대학 핵의학교실) ;
  • 이규보 (경북대학교 의과대학 핵의학교실) ;
  • 황기석 (경북대학교 의과대학 핵의학교실) ;
  • 김보완 (경북대학교 의과대학 내과학교실) ;
  • 이인규 (계명대학교 의과대학 내과학교실)
  • Published : 1991.05.31

Abstract

Multiple endocrine neoplasia type 2 (MEN type 2, Sipple's syndrome) is a rare disorder characterized by the association of medullary carcinoma of the thyroid, parathyroid hyperplasia and can be diagonsed in early stage of the disease by meticulous screening tests of the family. This case report describes the location and categorization of tumors using $^{99m}Tc-pertechnetate,\;^{131}I-NaI,\;^{99m}Tc-pentavalent(V)$, DMSA $^{131}I-MIBG$ scans in two cases of MEN type 2 occurred in a 32-year old women and her 29-year old brother. In MEN type 2, we think, combined use of $^{99m}Tc-(V)-DMSA,\;^{99m}Tc-pertechnetate\;and\;^{131}I-MIBG$ may be useful for the categorization of tumor mass lesions and planning appropriate therapy.

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