대한핵의학회지 (The Korean Journal of Nuclear Medicine)

대한핵의학회 (The Korean Society of Nuclear Medicine)
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강직성 척추염에서 $^{99m}Tc-MDP$ 골스캔의 임상적 의의

Clinical Significance of Bone Scan with $^{99m}Tc-MDP$ in Ankylosing Spondylitis

  • 김덕윤 (경희대학교 의과대학 내과학교실) ;
  • 김상은 (서울대학교 의과대학 내과학교실) ;
  • 이동수 (서울대학교 의과대학 내과학교실) ;
  • 정준기 (서울대학교 의과대학 내과학교실) ;
  • 이명철 (서울대학교 의과대학 내과학교실) ;
  • 조보연 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실) ;
  • 강흥식 (서울대학교 의과대학 방사선과학교실)
  • Kim, Deog-Yoon (Department of Internal Medicine, Kyung Hee University, College of Medicine) ;
  • Kim, Sang-Eun (Department of Internal Medicine, Seoul National University, College of Medicine) ;
  • Lee, Dong-Soo (Department of Internal Medicine, Seoul National University, College of Medicine) ;
  • Chung, June-Key (Department of Internal Medicine, Seoul National University, College of Medicine) ;
  • Lee, Myung-Chul (Department of Internal Medicine, Seoul National University, College of Medicine) ;
  • Cho, Bo-Youn (Department of Internal Medicine, Seoul National University, College of Medicine) ;
  • Koh, Chang-Soon (Department of Internal Medicine, Seoul National University, College of Medicine) ;
  • Kang, Heung-Sik (Department of Radiology, Seoul National University, College of Medicine)
  • 발행 : 1991.05.31
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초록

To evaluate the diagnostic usefulness of quantitative sacroiliac joint scintigraphy and its clinical significance in the ankylosing spondylitis, we measured SIS ratio (Sacroiliac Joint/Sacrum Uptake ratio) by region of interest method in 52 patients with ankylosing spondylitis. As compared with radiological grade, SIS ratio was significantly elevated in the early stage of ankylosing spondylitis and returned to normal range in the late stage. Scintigraphic finding of focal uptakes of radiotracer at multiple spinal apophyseal joints was characteristic and proximal large joints were more involved than distal joints. The incidence and extent of the arthropathy revealed by scnitigraphy exceeded that which was clinically evident, and scintigraphy was more sensitive to detect symptomatic lesion than radiography. Therefore, it is suggested that bone scan is useful for the early diagnosis and the assessment of clinical activity of involved joints of ankylosing spondylitis.

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