Journal of the Korean Chemical Society (대한화학회지)

Korean Chemical Society (대한화학회)
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Synthetic Studies on the Nucleophilic Addition of Cysteine and Thiophenol to ${\alpha}$,N-Diphenylnitrone Derivatives

${\alpha}$,N-Diphenylnitrone 유도체에 대한 Cysteine 및 Thiophenol의 친핵성 첨가물에 관한 연구

  • Tae-Rin Kim (Department of Chemistry, Korea University) ;
  • Sang-Yong Pyun (Department of Chemistry, Korea University) ;
  • Man-So Han (Department of Chemistry, Korea University) ;
  • Kwang-Il Lee (Department of Chemistry, Kyungki University)
  • Published : 1991.06.20
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Abstract

Four thiazolidines and following five new compounds were prepared by the addition reaction of cysteine and thiophenol to ${\alpha}$,N-diphenylnitrones, respectively ; ${\alpha}$,thiophenoxy-benzylidene aniline ;${\alpha}$,thiophenoxy-p-hydroxybenzylidene aniline ; ${\alpha}$,thiophenoxy-p-chlorobenzylidene aniline ;${\alpha}$,thiophenoxy-p-methoxybenzylidene aniline ; ${\alpha}$,thiophenoxy-p-nitrobenzylidene aniline. The structure of these compounds were confirmed by the elemental analysis, UV-, IR-and NMR-spectra.

${\alpha}$,N-diphenylnitrone에 cysteine과 thiophenol을 반응시켜 4개의 thiazolidine과 다음의 5가지 새로운 화합물을 합성하였다. ${\alpha}$,thiophenoxy-benzylidene aniline : ${\alpha}$, thiophenoxy-p-hydroxybenzylidene aniline : ${\alpha}$,thiophenoxy-p-chlorobenzylidene aniline : ${\alpha}$,thiophenoxy-p-methoxybenzylidene aniline : ${\alpha}$,thiophenoxy-p-nitrobenzylidene aniline. 이 화합물들의 구조는 원소분석, UV-, IR 및 NMR- 스펙트럼에 의해 확인하였다.

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