Bulletin of the Korean Chemical Society

  • 제12권6호
  • /
  • Pages.604-606
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  • 1991
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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C-Glucuronide from O-Glucuronyl Trichloroacetimidate

  • 발행 : 1991.12.20
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초록

From O-glucuronyl trichloroacetimidate (4) and ${\Delta}^6$-tetrahydrocannabinol (5), the C-glucuronide of ${\Delta}^6-tetrahydrocannabinol({\Delta}^6-THC)$ (7) was obtained using mild Lewis acid catalysis. The known method for the synthesis of C-glucuronide from 1-O-unprotected glucuronide provided low chemical yields. The C-glucuronide of ${\Delta}^6-THC$ was obtained through inversion of configuration at the anomeric center in O-glucuronyl trichloroacetimidate (4).

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참고문헌

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피인용 문헌

  1. The synthesis of O-glucuronides vol.15, pp.2, 1991, https://doi.org/10.1039/a815173y