Archives of Pharmacal Research
- Volume 14 Issue 2
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- Pages.99-102
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- 1991
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Analysis of Alkaloids in the Seeds of Zizyphus jujuba by High Performance Liquid Chromatography
- Park, Man-Ki (College of Pharmacy, Seoul National University) ;
- Park, Jeong-Hill (College of Pharmacy, Seoul National University) ;
- Shin, Young-Geun (College of Pharmacy, Seoul National University) ;
- Cho, Kyung-Hee (College of Pharmacy, Seoul National University) ;
- Han, Byung-Hoon (Natural Products Research Institute, Seoul Nationl University) ;
- Park, Myung-Hwan (Korea Research Institute of Chemical Technology)
- Published : 1991.06.01
Abstract
A hight performance liquid chromatographic methods was developed for the seperation and determination of seven alkaloids in "sanjoin" (the seeds of Zizyphus jujuba Rhamnaceae), a plant with potent sedative activity. A reverse phase system of Lichrosorb RP-Select B column and 0.05 M potassium phosphate buffer (pH = 3.5)-acetonitrile with gradient elution was employed. Two known alkaloids, juzirine and lysicamine, were newly isolated fom "sanjoin"."sanjoin".oin&".ot;.
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