Radiation Oncology Journal
- 제9권2호
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- Pages.253-263
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- 1991
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
간외담도종양에서 방사선치료의 역할
The Role of Radiotherapy in the Treatment of Extrahepatic Bile Duct Carcinoma
- 신현수 (연세대학교, 연세암센터, 치료방사선과학교실) ;
- 김귀언 (연세대학교, 연세암센터, 치료방사선과학교실) ;
- 이형식 (연세대학교, 연세암센터, 치료방사선과학교실) ;
- 서창옥 (연세대학교, 연세암센터, 치료방사선과학교실) ;
- 노준균 (연세대학교, 연세암센터, 치료방사선과학교실) ;
- 이종태 (연세대학교, 연세암센터, 방사선과학교실)
- Shin Hyun Soo (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
- Kim Gwi Eon (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
- Lee Hyung Sik (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
- Suh Chang Ok (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
- Loh John JK (Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine) ;
- Lee Jong Tae (Department of Radiology, Yonsei University College of Medicine)
- 발행 : 1991.12.01
초록
1985년부터 1990년까지 연세대학교, 연세암센터 치료방사선과에 내원하였던 27명의 간외담도종양환자를 대상으로 외부방사선조사 및 관내 근접조사(intraluminal brachytherapy)를 병용하였을 경우 적절한 국소관해율을 얻을 수 있는지에 대한 후향적 분석을 하였고 이러한 치료방법에 대한 결과를 불완전한 절제술후 방사선치료를 시행한 군의 치료성적과 비교분석하였다. 16명은 남성이었고 11명은 여성이었으며, 평균나이는 58세(
Twenty-seven patients with unresectable extrahepatic bile duct carcinoma (n=21) or with microscopic evidence of tumor rest after aggressive surgery for extrahepatic bile duct carcinoma (n=6) between 1985 and 1990 were given radiotherapy consisting intentionally external radiotherapy and/or intraluminal therapy using Gamma-Med 12i (192-Ir) high dose rate (HDR) remote control afterloading system following bile drainage procedures and Gianturco stent insertion. The objectives of this study has been to assess the feasibility and effects on survival of a combination of external radiotherapy and brachytherapy with which we hope to achieve optimal loco-regional control for patients with unresectable extrahepatic bile duct tumors. Sixteen patients were men and eleven were women, and the mean age was 58 years (34-70). 10MV X-ray was used for radiation therapy, with the total dose ranging from 45 Gy to 55 Gy, and intraluminal brachytherapy performed after external radiotherapy, with the dose of total 15 Gy. The minimum follow up was 12 months. Failure were predominantly local-regional, without distant failure. Median survival was 10 months; 2-year actuarial survival rates was