Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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The Study on the Effective Components in Various Parts of Luffa cylindrica and Development for Removal of the Flesh from its Fruits(III) -Cytotoxic Activity of Leaf, Stem and Seed Extracts against L1210 Cells and Antibacterial Activity against Streptococcus mutans OMZ176-

수세미오이의 부위별 유효성분 조사 및 사과락의 육질제거에 관한 연구(III) -잎, 줄기 및 종자의 L1210세포에 대한 세포독성과 충치균에 대한 항균작용-

  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Chi, Jong-Myung (College of Pharmacy, Chungnam National University) ;
  • Chang, Ki-Woon (College of Agriculture, Chungnam National University)
  • Published : 1991.12.30
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Abstract

The cytotoxic and antibacterial activities of the leaf, the stem and the seed extracts of Luffa cylindrica were evaluated against L1210 cells and Streptococcus mutans OMZ176, respectively. Among hexane, ether, butanol and water fractions, the ether fraction demonstrated the most potent cytotoxic activity, and the $ED_{50}$ values of the ether extract from the leaf, the stem and the seed were 3.5, 3.7 and $13.7{\mu}g/ml$, respectively. Meanwhile, the other fractions showed negligible effect. Separately, it was found that the antibacterial activity of the respective fraction from three parts was insignificant.

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