대한약리학회지 (The Korean Journal of Pharmacology)
- 제27권1호
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- Pages.69-80
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- 1991
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- 0377-9459(pISSN)
$Fe^{2+}$ 에 의한 지질 과산화에 있어서 Quercetin과 Rutin의 억제 작용
Inhibitory Actions of Quercetin and Rutin on $Fe^{2+}-induced$ Lipid Peroxidation
- Chung, Jin-Hee (Department of Pharmacology, College of Medicine, Chung-Ang University) ;
- Lee, Chung-Soo (Department of Pharmacology, College of Medicine, Chung-Ang University) ;
- Shin, Yong-Kyoo (Department of Pharmacology, College of Medicine, Chung-Ang University) ;
- Lee, Kwang-Soo (Department of Pharmacology, College of Medicine, Chung-Ang University)
- 발행 : 1991.06.30
초록
Iron(II)에 의한 마이크로좀의 지질 과산화에 미치는 quercetin과 rutin의 억제 효과를 iron의 산화중에서 생성되는 산소 라디칼에 대한 제거 작용과 iron에 대한 킬레이트 작용에 관하여 관찰하였다.
Inhibitory effects of quercetin and rutin on lipid peroxidation of microsomes caused by iron(II) were investigated with respect to the scavenging action for oxygen radicals produced during oxidation of iron and the chelating action for iron. Lipid peroxidation by