남성불임 환자에서 Tray Agglutination Test 및 Indirect Immunobead Test를 이용한 항정자항체에 관한 연구

Antisperm Antibodies in Infertile Males as Detected by Tray Agglutination Test and Indirect Immunobead Test

Sera from 95 infertile males males were assayed for antisperm antibodies using the Tray Agglutination Test(TAT) and indirect Immunobead Test(IBT). The correlation between antisperm antibodies and seminal analysis in infertile men was evaluated, and the TAT was compared with new indirect IBT. The results were obtained as follows. 1. Positive rate for antisperm antibodies was high in azoospermia, oligoasthenospermia, pyo-spermia, in order, Especially in obstructive azoospermia, the rate was the highest in both methods 2. Positive rates for antisperm antibodies in TAT was higher than indirect IBT. 3. Among the isotypes of the immunoglobulins, IgG were most prevalent. IgG and IgA were bound predominantly to the head and IgM predominantly to the tail up.