The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Intraarterial Scintigraphy in Recurrent Cervix Cancer - The Evaluation of Radionuclide Therapeutic Trials -

자궁경부재발암 환자의 국소동맥 주입식 동위원소 검사 -방사성 동위원소의 치료시도를 위한 평가-

  • Kim, Eun-Young (Department of Diagnostic Radiology, Yonsei University College of Medicine) ;
  • Suh, Jin-Suck (Department of Diagnostic Radiology, Yonsei University College of Medicine) ;
  • Park, Chang-Yun (Department of Diagnostic Radiology, Yonsei University College of Medicine) ;
  • Lee, Jong-Tae (Department of Diagnostic Radiology, Yonsei University College of Medicine) ;
  • Yoo, Hyung-Sik (Department of Diagnostic Radiology, Yonsei University College of Medicine)
  • 김은영 (연세대학교 의과대학 진단방사선과학교실) ;
  • 서진석 (연세대학교 의과대학 진단방사선과학교실) ;
  • 박창윤 (연세대학교 의과대학 진단방사선과학교실) ;
  • 이종태 (연세대학교 의과대학 진단방사선과학교실) ;
  • 유형식 (연세대학교 의과대학 진단방사선과학교실)
  • Published : 1990.11.25
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Abstract

We performed 17 intraarterial scintigraphies in six patients with recurrent cervix cancer. With Seldinger method, the agent (four different radiopharmaceuticals) was perfused at the same speed of infusion of anticancer drugs (25 cc/hour) through internal iliac artery. There were four different radiopharmaceuticals; I-131-Lipiodol, Tc (Technetium)-99m-HSa (Human Serum Albumin), $^{99m}Tc-Sucralfate$ and $^{99m}Tc-MAA$ (Macroaggraegated Albumin). We evaluate the distribution pattern of radioactivity by the use of ratio of Tumor/Extratumor uptake (T/ET ratio). Our results reveals that $^{99m}Tc-MAA$ scan showed the highest T/ET ratio and the other were not ideal agents for intraarterial therapy of recurrent cervix cancer. In conclusion, an ideal radioisotope and tracer which can block capillary, for example MAA, should be re-evaluated or produced in order to treat the patient with recurrent cervix cancer.

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