The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Serum CEA Related to Clinical Status and Outcome of Treatment in Stomach Cancer

위암환자에서 임상적 양상 및 치료에 따른 혈청 CEA치의 변화에 관한 연구

  • Chang, Se-Ho (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Lee, Sam-Cheol (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Kim, Kun-Young (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Lee, Won-Joo (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Choi, Seong-Lan (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Lee, Jong-Suk (Department of Internal Medicine, College of Medicine, Gyeongsang National University) ;
  • Jung, Sun-Il (Department of Internal Medicine, College of Medicine, Gyeongsang National University)
  • 장세호 (경상대학교 의과대학 내과학교실) ;
  • 이삼철 (경상대학교 의과대학 내과학교실) ;
  • 김건용 (경상대학교 의과대학 내과학교실) ;
  • 이원주 (경상대학교 의과대학 내과학교실) ;
  • 최성란 (경상대학교 의과대학 내과학교실) ;
  • 이종석 (경상대학교 의과대학 내과학교실) ;
  • 정순일 (경상대학교 의과대학 내과학교실)
  • Published : 1990.11.25
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Abstract

Serum carcinoembryonic antigen (CEA) levels were measured by radioimmunoassay in 82 patients with stomach cancer and were related to their clinical status and to the response to therapeutic modalities. Serum CEA in patients over 40 years of age was higher (p < 0.05) than that of younger age group and was higher (p 앞 0.0025) in patients with advanced stages (IIII and IV) than in patients with earlier stages (EGC and stage II). No significant differences in serum CEA levels were seen between the tumor cell types. In 9 patients who underwent successful radical resection of the cancer, serum CEA decreased significantly (p < 0.05) after surgery, whereas the changes in serum CEA levels after palliative surgery in other 7 patients were statistically insignificant (p > 0.01). Eleven patients who were given chemotherapy were followed up until death, the changes in their serum CEA levels were significant reverse-correlation (r=-0.72) with duration of survival.

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