Cited by
- ChemInform Abstract: New Aminothiazolyl Cephalosporins. Synthesis and Biological Evaluation of 7-(Alkoxyiminomethyl(2-aminothiazol-4-yl)acetamido)ceph-3-em-4- carboxylic Acids. vol.22, pp.28, 1990, https://doi.org/10.1002/chin.199128244
Bulletin of the Korean Chemical Society
- Volume 11 Issue 6
- /
- Pages.538-542
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- 1990
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- 0253-2964(pISSN)
- /
- 1229-5949(eISSN)
DOI QR Code
New Aminothiazolyl Cephalosporins. Synthesis and Biological Evaluation of 7-[Alkoxyiminomethyl(2-aminothiazol-4-yl)acetamido]ceph-3-em-4-carboxylic Acids
-
Koh, Hun-Yeong
(Chemistry Division, Korea Institute of Science and Technology)
;
- Kang, Han-Young (Chemistry Division, Korea Institute of Science and Technology) ;
-
Choi, Kyung-Il
(Chemistry Division, Korea Institute of Science and Technology)
;
- Chang, Moon-Ho (Chemistry Division, Korea Institute of Science and Technology)
- Published : 1990.12.20
Abstract
New aminothiazolyl cephalosporins with alkoxyiminomethyl(2-aminothiazol-4-yl)acetyl substituents at 7-position of cephems were synthesized starting from (2-aminothiazol-4-yl)acetate via one carbon homologation followed by acylation with 7-aminoceph-3-em-4-carboxylic acid derivatives. These new aminothiazolyl cephalosporins exhibit promising in vitro activities against various strains including Gram positive bacteria.
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