Bulletin of the Korean Chemical Society

  • 제11권3호
  • /
  • Pages.228-231
  • /
  • 1990
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Synthesis of Novel Acyclonucleosides ; Reactions of Diazinone Heterocycles with 4-Bromoacetoacetic acid and Methyl 4-bromoacetoacetate

  • Sam-Yong Choi (Department of Chemistry, Gyeongsang National University) ;
  • Sung Chul Shin (Department of Chemistry, Gyeongsang National University) ;
  • Young-Jin Yoon (Department of Chemistry, Gyeongsang National University)
  • 발행 : 1990.06.20
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초록

Some substituted pyridazin-6-ones(1-4) and two uracils(10,12) have been converted to the corresponding $N_1$-(2-oxopropyl)pyridazine-6-ones(6-9), 1,3-bis(2-oxopropyl)-5-fluorouracil(11) and 2-(2-oxopropylthio)uracil(13) respectively by reaction with 4-bromoacetoacetic acid. Also, 4,5-dichloro-1-(3-carbomethoxy-2-oxopropyl)pyrida zin-6-one(15) and 4,5-dichloro-3-nitro-1-(3-carbomethoxy-2-oxopropyl)pyridazin-6-one(16) was synthesized from the corresponding pyridazin-6-ones(1,2) and methyl 4-bromoacetoacetate.

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피인용 문헌

  1. ChemInform Abstract: Synthesis of Novel Acyclonucleosides; Reactions of Diazinone Heterocycles with 4‐Bromoacetoacetic Acid and Methyl 4‐Bromoacetoacetate. vol.21, pp.48, 1990, https://doi.org/10.1002/chin.199048280
  2. Synthesis of novel acyclonucleosides. Reactions of 1-(2-oxopropyl)pyridazin-6-ones vol.28, pp.2, 1990, https://doi.org/10.1002/jhet.5570280234
  3. Synthesis of novel pyridazine acyclonucleosides vol.31, pp.5, 1990, https://doi.org/10.1002/jhet.5570310517
  4. Synthesis of novelN-acyclonucleosides: Benzotriazole, benzothiazinone and pyridooxazinone acyclonucleosides vol.33, pp.2, 1996, https://doi.org/10.1002/jhet.5570330217