한국식품영양과학회지 (Journal of the Korean Society of Food Science and Nutrition)
- 제19권2호
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- Pages.150-155
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- 1990
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- 1226-3311(pISSN)
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- 2288-5978(eISSN)
식이성 비타민 E가 카페인 투여 흰쥐의 체내 지질과산화에 미치는 영향
Effects of Dietary Vitamin E on the Lipid Peroxidation in Rats Fed Caffeine
초록
카페인 투여 환쥐의 체내 지칠파산화에 미치는 식이성 비타민 E의 영향을 검토하고자, 흰쥐에게 카페인 수용액(0,
This experiment was undertaken to investigate the effect of dietary vitamin E on the lipid peroxidation in the caffeine-fed rats. Male Sprague-Dawley rats were fed for 6 weeks diets containing one of three levels of dietary vitamin E(30, 500 or 1,000mg/kg diet) with 1,000mg caffeine per liter in drinking water but control group was only given without caffeine. Net weight gain food intake caffeine intake and hematocrit were not significantly different. In rats fed caffeine liver lipid peroxidation level was slightly increased but significantly lower in rats fed 1, 000mg vitamin E/kg diet than in those fed 500mg vitamin E/kg diet. Glutathione peroxidase activity in rats fed caffeine was higher than in the control And the higher dietary vitamin E level the lower glutathione peroxidase activity. Catalase activity was significantly increased in the caffeine-fed rats. however xanthine oxidase activity was not afexcted in all experimental groups.
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