한국동물학회지 (The Korean Journal of Zoology)
- 제33권2호
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- Pages.158-165
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- 1990
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- 0440-2510(pISSN)
배양 근원세포의 분화에 따른 Calpain의 활성 및 양적 변화
Alterations in the Level of Calpain During the Differentiation of Chick Embryonic Muscle Cells in Culture
초록
Calpain은
Proteolytic activity of calpain was found to increase as myoblast fusion proceeds. At 60 hr after cell seeding, lis activity reached to a maximal level and then slighdy decreased thereafter. Similarly, the protein level of calpain reached to a maximal level just proir to the initiation of fusion and remained elevated upon prolonged culture as analyzed by immunoblol using anti-calpain antiserum. These results suggest that the synthesis of calpain is regulated during myogenesis and its proteolytic activity may be related with the process of myoblasts fusion.
키워드