Synthesis of Certain Uracil-6-yl or Tetrazol-5-ylpyrazolin-5-one and Pyrazole Derivatives as Potential Anti-inflammatory Agents

  • Moustafa, M.A (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • Eisa, H.M (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • El-Emam, A.A. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • Metwally, M.A. (Department of Chemistry, Faculty of Sciences, University of Mansoura)
  • Published : 1990.06.01

Abstract

Certain pyrazolin-5-one and pyrazole derivatives bearing uracil-6-yl or tetrazol-5-yl moiety in position 1 have been synthesized. The anti-inflammatory activity of six representative compounds have been tested and the results are reported.

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