Effect of Acidic Polysaccharide of Korean Red ginseng on Lipolytic Action of Toxohormone-L from Canceroils Ascites Flilid

고려인삼의 산성다당체 성분이 암독소 호르몬-L의 지방질 분해작용에 미치는 영향

Toxohormone-L is a lipolytlc factor, found in ascites fluid of sarcoma 180-bearing mice and of patients with hepatoma. A substance that inhibited the lipolytic action of Toxohormone-L was isolated from Korean red ginseng powder. This substance had a pectin-like a-1,4-polygalacturonan backbone with some acetoxyl groups, and so was an acidic polysaccharide. Acidic polysaccharide was found to inhibit significantly toxohormone-L-induced lipolysis at its concentration of 10$\mu\textrm{g}$/ml.