Effect of Ginseng Extracts on Photosensitized Peroxidation of Human Erythrocyte Ghosts

Erythrocyte Ghost의 광산화반응에 미치는 인삼추출물의 영향

  • Baek, Tae-Hong (Department of Chemistry, College of Natural Sciences, Hanyang University) ;
  • Cheon, Hyeon-Ja (Department of Chemistry, College of Natural Sciences, Hanyang University) ;
  • Gang, Byeong-Su (Department of Chemistry, College of Natural Sciences, Hanyang University)
  • 백태홍 (한양대학교 자연과학대학 화학과) ;
  • 천현자 (한양대학교 자연과학대학 화학과) ;
  • 강병수 (한양대학교 자연과학대학 화학과)
  • Published : 1990.04.01

Abstract

The photooxidation of human erythrocyte ghosts has been studied and the effects of ginseng water extract on it have been investigated. In the presence of photosensitizer, rose bengal, human erythrocyte ghosts have caused photooxidation by lO2 and produced lip)id hydroperoxides. Ginseng water extract and d-${\alpha}$-tocofherol have inhibited photooxidation, ,whereas ascorbic acid has developed in low concentrations but inhibited in high concentrations. On the other hand, amounts of lipid hydroperoxide produced by photooxidation were decreased by addition of catalase after irradiation and according to sequential addition of ginseng water extract into it, the formation of lipid hydrolleroxide was decreased simultaneously.

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