Radiation Therapy of Nasopharyngeal Carcinoma KCCH Experience ($1964\~1984$)

비인강암의 방사선 치료

  • Koh Kyoung Hwan (Department of Therapeutic Radiology, Korea Cancer Center Hospital) ;
  • Park Woo Yoon (Department of Therapeutic Radiology, Korea Cancer Center Hospital) ;
  • Cho Chul Koo (Department of Therapeutic Radiology, Korea Cancer Center Hospital) ;
  • Yoo Seong Yul (Department of Therapeutic Radiology, Korea Cancer Center Hospital) ;
  • Shim Youn Sang (Department of Otolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital) ;
  • Oh Kyung Kyoon (Department of Otolaryngology-Head and Neck Surgery, Korea Cancer Center Hospital)
  • 고경환 (원자력병원 치료방사선과) ;
  • 박우윤 (원자력병원 치료방사선과) ;
  • 조철구 (원자력병원 치료방사선과) ;
  • 류성렬 (원자력병원 치료방사선과) ;
  • 심윤상 (원자력병원 이비인후과) ;
  • 오경균 (원자력병원 이비인후과)
  • Published : 1990.06.01

Abstract

Total of 154 patients of pathologically proven and previously untreated nasopharyngeal carcinoma who were treated in the Department of Therapeutic Radiology, Korea Cancer Center Hospital during the period from 1964 to 1984 were analyzed. Minimal follow-up period of survivors was 3 years. Thirteen percent of the patients had $T_4$ primary lesions and $65\%$ had stage IV disease. Total radiation dose to the primary site was $1550\~1750$ ret in 82 and above 1750 ret in 72 patients. Local control was obtained in $79\%$ of patients. Significant prognostic factors for the survival were tumor dose (above vs. below 1750 ret), age (below vs. above 30 years), stage (AJCC I-III vs. IV), T stage ($T_1\;vs.\;T_2-4$), and N stage (NO vs. $N^+$).

1964년부터 1984년까지 원자력병원 치료방사선과에서 비인강암으로 근치적 목적의 방사선치료를 받은 154명의 환자에 대한 임상적 특성과 치료결과를 분석하였다. 생존자의 최소추적기간은 3년이었다. 환자의 $13\%$$T_4$의 원발병소를 가졌고, $65\%$가 AJCC병기 제 4 기였다. 병소부위의 총방사선량은 82명에서 $1550\~1750$ret였고, 72명에서 1750ret이상이었다. 국소적 완전관해율은 $79\%$이었다. 유의한 예후인자로는 방사선량(1750ret이상 또는 이하), 나이 (30세이하 또는 이상), 병기 (AJCC 제 $1\~3$기 또는 제 4기), 원발병 소정도 ($T_1$ 또는 $T_2\~T_4$병기), 경부임파절유무 (NO 또는 $N^+$)이었다.

Keywords