생약학회지 (Korean Journal of Pharmacognosy)
- 제21권1호
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- Pages.74-82
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- 1990
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
천연 Furanocoumarin 유도체들이 간의 Cytochrome P-450 효소계에 미치는 작용기전
The Mode of the Activity of Naturally Occurring Furanocoumarins on Hepatic Cytochrome P-450 Enzyme System
- Shin, Kuk-Hyun (Natural Products Research Institute, Seoul National University) ;
- Woo, Won-Sick (Natural Products Research Institute, Seoul National University)
- 발행 : 1990.03.30
초록
The effects of naturally occurring furanocoumarins on cytochrome P-450 have been investigated in rat liver microsomes. Incubation of microsomes with an NADPH-generating system and four furanocoumarins such as imperatorin, isoimperatorin, phellopterin and byakangelicin at
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