Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Assay of Antimutagenic Activities of Vegetable Plants

식용식물(食用植物)의 항변이원성(抗變異原性)에 관한 연구(硏究)

  • Seo, Jung-Sook (Graduate School of Public Health, Seoul National University) ;
  • Lee, Young-Wook (Graduate School of Public Health, Seoul National University) ;
  • Suh, Nan-Joo (Natural Products Research Institute, Seoul National University) ;
  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University)
  • Published : 1990.03.30
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Abstract

Potential antimutagenic activities of vegetable plants were investigated. 24 vegetables which are frequently consumed by Korean people were extracted with 70% ethyl alcohol to prepare the extract samples. Then those samples were added to the culture media containing mitomycin C($O.3\;{\mu}g/ml$) and the SOS-Chromotest was performed. Positive control, mitomycin C alone, showed about 330 units of ${\beta}$-galactosidase activities. Among 24 vegetable samples, Saxifraga oblougifolia Nakai (취나물, Saxifragaceae) and Platycodon grandiflorum A. De Candolle(도라지, Campanulaceae) showed 136 and 155 units, respectively when mitomycin C was treated. These results indicate that Saxifragae Herba and Platycodi Radix possess protecting action from mutagenic activity produced by mitomycin C.

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