Synthesis of Adriamycin-related System (1) -Synthesis of the Derivative of Tetrahydrobenzo(b)phenazine as a Potential Isostere of Anthracyclinone-

아드리아마이신의 유사제제 합성 (1) -안트라싸이클리논의 Isostere 로서 Tetrahydrobenzo(b)phenazine 유도체의 합성-

7,8-Dihydro-6,11-dihydroxy-9(10H)benzo(b)phenazinone was prepared from 1,2,3,4-tetra-hydrophenazine as a potential isostere of anthracyclinone. The attempts to functionalize at $C_9$ were not successful due to the unstability of the above ketone.