Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Enzymatic Hydrolysis of$\beta$-Lactam Esters by PLE

  • Published : 19890200
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Abstract

Pig Liver Esterase (PLE) which has been known to cleave a broad range of diesters to prepare stereoselective enantiomers is applied to hydrolysis of ${\beta}-lactam$ esters imparting the corresponding acids in various yields.

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References

  1. Enzymes as Catalysts in Organic Synthesis M. Ohno;S. Kobayashi;Adachi;M. P. Schneider(ed.)
  2. Nippon Kagaku Kaishi v.9 A. Hazato;T. Tanaka;T. Toru;N. Okamura;K. Bannai;S. Sugiura;K. Manabe;S. Kurozumi
  3. Recent Advances in the Chemistry of ${\beta}$-Lactam Antibiotics A. H. Shingler;N. G. Weir;J. Elks(ed.)
  4. Tetrahedron Lett. v.21 D. G. Melillo;I. Shinkai;T. Liu;K. Ryan;M. Sletzinger

Cited by

  1. E/Z-Diastereoselektive enzymatische Hydrolyse von Estern und Diestern vol.105, pp.4, 1989, https://doi.org/10.1002/ange.19931050429