Toxicological Research
- Volume 5 Issue 2
- /
- Pages.123-133
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- 1989
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
SUBACUTE TOXICITY OF HANTABAX (HFRS-VACCINE) IN RATS
-
Moon, Chang-Kiu
(College of Phamacy Seoul National University)
;
- Park, Kwang-Sik (College of Phamacy Seoul National University) ;
- Mock, Myung-Soo (College of Phamacy Seoul National University) ;
- Jung, Myung-Kiu (College of Phamacy Seoul National University) ;
- Kim, Ji-Young (College of Phamacy Seoul National University) ;
-
Lee, Yong-Soon
(College of Veterinary, Medicine, Seoul National University)
;
- Jeong, Ja-Young (College of Veterinary, Medicine, Seoul National University) ;
- Hur, Gyeung-Haeng (College of Veterinary, Medicine, Seoul National University) ;
-
Kang, Kyung-Sun
(College of Veterinary, Medicine, Seoul National University)
;
- Hwang, Gui-Seo (College of Phamacy Seoul National University) ;
- Kim, Seong-Gon (College of Phamacy Seoul National University) ;
- Won, Hyun-Soon (College of Phamacy Seoul National University)
- Published : 1989.12.01
Abstract
Subacute toxicity of Hantabax, epidemic hemorrhagic fever vaccine, was investigated in Sprague-Dawley rats with subcutaneous injection. Any significant toxic clinical symptom was not observed in the treated rats during the experimental period. Macroscopic examination on the organs of tested animals showed no abnormal findings. On autopsy, no significant changes were found in organs examined.