Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)
- Volume 10 Issue 2
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- Pages.89-90
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- 1989
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- 1229-0807(pISSN)
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- 2288-9396(eISSN)
우리 학회 활성화 방안
Abstract
To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased.
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