Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Synthesis and Antibacterial Activities of Triphenyltin Cephalosporins

  • Park, Sang-Woo (Organic Chemistry Laboratory, Korea Advanced Institute of Science and Technology) ;
  • Kim, You-Seung (Organic Chemistry Laboratory, Korea Advanced Institute of Science and Technology) ;
  • Chung, Young-Keun (Department of Chemistry, Seoul National University)
  • Published : 1989.09.01
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Abstract

Although it has been known that organometallic $\beta$-lactam compounds improve the resistance to $\beta$-lactamases as well as their pharmacological activities, only a few results on organometallic $\beta$-lactam antibiotics were reported. In the course of our extensive study on the development of new cephalosporins, we were interested in organotin compounds since they show some biological activities.

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