Journal of Ginseng Research

The Korean Society of Ginseng (고려인삼학회)
권호 표지

Growth Promoting Activity of a Macromolecular Fraction from Fresh Ginseng

수삼 고분자 분획의 성장촉진활성

  • Eun, Song-Myung (Biochemistry Department, The Chinese University of Hong Kong) ;
  • Hung, Ng-Kam (Biochemistry Department, The Chinese University of Hong Kong) ;
  • Nam, Leung-Kwok (Biochemistry Department, The Chinese University of Hong Kong) ;
  • Cheung, Kong-Yum (Biochemistry Department, The Chinese University of Hong Kong)
  • Published : 1989.12.01
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Abstract

A macromolecular fraction from fresh ginseng root containing mainly polysaccharide showed mild mitogenic activity in human cord blood lymphocytes. 2) When lymphocytes were transformed by Con A or PHA, this fraction could greatly enhance the activity of these lectin mitogens, thus showing a potentiation effect. 3) Although this macromolerular fraction contains saponin and is susceptible to trypsin digestion, it is probably a peptido-glycan in nature on account of its important carbohydrate content and thermal stability. 4) This fraction could not support cancer cell (EAT, K562) growth : its inhibitory effect on these cells remains to be explored.

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