Radiation Oncology Journal
- Volume 7 Issue 1
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- Pages.15-22
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- 1989
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
Skin Radioprotector (Diethone) Modifying Dermal Response of Radiation on Rats
방사선 보호제(Diethone)의 랫드 피부반응에 대한 수식작용
- Hong, Seong-Eon (Department of Therapeutic Radiology, College of Medicine, Kyung Hee University) ;
- Urahashi, Shingo (Department of Radiology, Nihon University, School of Medicine) ;
- Kamata, Rikisaburo (Department of Radiology, Nihon University, School of Medicine)
- 홍성언 (경희대학교 의과대학 치료방사선과학교실) ;
- ;
- Published : 1989.06.01
Abstract
Investigations were carried out into the time-and dose-related changes in acute skin reaction following graded single dose (20,30 and 40 Gy) of x-ray irradiation in Wistar rats, in order to evaluate the radioprotective effect of Diethon on skin. For the duration of skin response over 1. 5 score in dose of 40 Gy, the Diethone group of 24.7 days was significantly different (p<0.02) from that of control (29.8 days) and vaseline (29.2 days) groups, it was
Diethone의 피부에 대한 방사선 보호작용을 평가하기 위하여 Wistar계 랫드에 단일 X-선(20, 30, 40 Gy) 조사 후 시간경과와 선량변화에 따른 급성 피부반응을 연구하였다. 40Gy 선량에서 Diethone군의 피부반응기간은 24.7일로 대조군(29.8일)과 바셀린(29.2일) 투여군에 비하여 약