Enantiomer의 분리에 이용될 수 있는 Chelate Resin의 개발(제 3보)-Copper(II) L-Proline Chelate Resin의 제조 및 Enantiomer 분리-

Development of Optically Active Chelate Resin for Direct Resolution of Enantiomers(III)-Synthesis of Copper(II) L-Proline Chelate Resin and Resolution of Enantiomers-

A metal complex, copper (II) L-proline was chemically bound to ethylene glycol dimethacrylate and divinylbenzene crosslinked chloromethylated polystyrene and they were used as chiral chelate resin matrix for column chromatography to resolve enantiomers of DL-amino acids. The L-enantiomers eluted first and the degree of resolution on the polymer crosslinked with ethylene glycol dimethacrylate was superior to the polymer crosslinked with divinylbenzene.