Bulletin of the Korean Chemical Society

  • 제9권5호
  • /
  • Pages.295-298
  • /
  • 1988
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
권호 표지
DOI QR코드

DOI QR Code

Synthesis of Acyclic Nucleosides of 2-Thio-Pyrimidines and -Purines Using a New Coupling Agent of Lithium Bromide

  • Kim, Joong-Young (Department of Chemistry, Korea Advanced Institute of Science and Technology) ;
  • Kim, Yong-Hae (Department of Chemistry, Korea Advanced Institute of Science and Technology)
  • 발행 : 1988.10.20
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Acyclic nucleosides, 1-[[1,3-bis(benzyloxy)-2-propoxy]methyl]-2-thiopyrimidine, 9-[[1,3-bis(benzyloxy)-2-propoxy]methyl]-6-amino -2-thiopurine, 1-(2-acetoxyethoxymethyl)-2-thiopyrimidine, and 9-[[1,3-bis(benzyloxy)-2-propoxy]methyl]-6-amino -2-thiopurine have been synthesized by coupling pyrimidine and purine bases with acyclic acetates using a new coupling reagent of lithium bromide in the presence of trifluoro acetic acid in acetonitrile.

키워드

참고문헌

  1. J. Med. Chem. v.26 J. C. Martin;C. A. Dvorak;D. F. Smee;T. R. Matthews;J. P. H. Verheyden
  2. U. S. Patent., 4533032 J. C. Martin;J. P. H. Verhyden
  3. Nature. v.272 H. J. Schaffer;L. Beauchamp;P. de. Miranda;G. B. Elion;D. J. Bauer;P. Collins
  4. J. Med. Chem. v.24 A. Rosowsky;S. H. Kim;M. Wick
  5. Tetrahedron Lett. v.15 H. Verbruggen;B. Bennua
  6. Tetrahedron Lett. v.25 T. S. Lin;M. C. Liu
  7. J. Org. Chem. v.39 U. Niedballa;H. Vorbruggen
  8. Science v.207 Y. H. Kim;L. A. Pavelka;H. S. Mosher;F. A. Fuhrman;G. J. Fuhrman
  9. J. Natural Products v.44 Y. H. Kim;R. Nachman;L. Pavelka;H. S. Mosher;F. A. Fuhrman;G. J. Fuhrman
  10. Angew. Chem. v.77 E. Wittenburg
  11. J. Med. Chem. v.28 J. C. Martin;C. A. Jeffery;D. P. C. Miechael;M. A. Tlpple;D. F. Smee;T. R. Matthews;J. P. H. Verheyden

피인용 문헌

  1. ChemInform Abstract: Synthesis of Acyclic Nucleosides of 2‐Thio‐pyrimidines and ‐purines Using a New Coupling Agent of Lithium Bromide. vol.20, pp.16, 1988, https://doi.org/10.1002/chin.198916337
  2. Acyclonucleosides: Part 2. diseco -Nucleosides vol.68, pp.None, 1997, https://doi.org/10.1016/s0065-2725(08)60360-8