DOI QR코드

DOI QR Code

Halogenation of Resorcinol Derivatives

  • 백승화 (원광대학교 자연과학대학 화학과)
  • Published : 1988.02.20

Abstract

Several types of resocinols have been monobrominated in the ring in good yields with sodium bromide in the presence of 18-crown-6 on oxidation with m-chloroperbenzoic acid. Monoiodination takes place with 2'-(1-methylcyclohexen-3-yl)-5-(1,1-dimethylheptyl )-resocinol when sodium iodide is employed. This new reagent system, MX/18-crown-6/m-CPBA (M =$K^+, Na^+, X = Br^-, I^-X$ ), effects the regiospecific halogenation of activated aromatic ring over olefinic double bond.

Keywords

References

  1. Synthesis G. A. Olah;Y. D. Vankar;M. Arvanaghi;G. K. S. Prakash
  2. J. Am. Chem. Soc. v.10 Y. Ogata;K. Aoki
  3. Synthesis E. B. Merkushev;N. D. Simakhina;G. M. Koveshnikova
  4. J. Org. Chem. v.49 O. Lerman;Y. Tor;D. Hebel;S. Rozen
  5. J. Org. Chem. v.51 T. B. Patrick;D. L. Darling
  6. Vogel's Textbook of Practical Organic Chemistry(4th edition) B. S. Furniss;A. J. Hannaford;V. Rogers;P. W. G. Smith;A. R. Tatchell
  7. Doctoral thesis, The Hebrew Univ. of Jerusalem S. H. Baek
  8. Doctoral thesis, The Hebrew Univ. of Jerusalem M. Srebnik
  9. J. Am. Chem. Soc. v.96 D. J. Sam;H. E. Simmons
  10. J. Am. Chem. Soc. v.96 C. L. Liotta;H. P. Harris
  11. Tetrahedron Lett. R. N. Greene
  12. Tetrahedron Lett. M. J. Maskornick
  13. J. C. S. Chem. Comm. I. Belsky
  14. Can. J. Chem. v.61 A. Fischer;G. N. Henderson
  15. J. Chem. Soc. Perkin Trans. I M. Srebnik;R. Mechoulam;I. Yona

Cited by

  1. ChemInform Abstract: Halogenation of Resorcinol Derivatives. vol.19, pp.35, 1988, https://doi.org/10.1002/chin.198835108