Journal of the Korean Society of Tobacco Science (한국연초학회지)

The Korean Society of Tobacco Science (한국연초학회)
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The Mutagenic Activity of Some Medicinal Plant Extracts in Strain TA 08 of Salmonelle typhimurium

Salmonella typhimurium에 의한 생약 추출물의 돌연변이성 연구(II)

  • 김숙영 (한국인삼연초연구소 화학부) ;
  • 문자영 (한국인삼연초연구소 화학부) ;
  • 이동욱 (한국인삼연초연구소 화학부) ;
  • 박기현 (한국인삼연초연구소 화학부)
  • Published : 1988.06.01
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Abstract

The mutagenic activities of the pyrolysates(300, 600, 750 and 85$0^{\circ}C$) of extracts from four antitussive or expectorant medicinal plants(Daturae Folios, Scopoliae Rhizoma, Acori Rhisoma, and Schigandrae Fructus) were studied in the Ames Salmonella/microsomes test system. The pyrolyzate of Schizandrae Fructus did not show the mutagenicity to tester strain TA98 of Salmonella typhinurium. However, those of other medicinal Plants, Daturae Folium, Scopoliae Rhigoma and Acori Rhizoma, exhibited the mutagenic activity to this strain and the mutagenicity of them were decreased gradually to 70% of the initial activity according to time course after the preparation of the samples with DMSO.

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