한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
- 제3권3호
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- Pages.111-116
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- 1988
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- 1229-1153(pISSN)
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- 2465-9223(eISSN)
Antitumor Activity of Protein-Plysacharides Produced form Vibrio anguillarum
- Yu, Byeong-Ho (Department of Food science and Technology, Kyung-Sung University) ;
- Chi, Boung-Ho (Department of Food science and Technology, Kyung-Sung University) ;
- Kim, Dong-Suck (Department of Food science and Technology, Kyung-Sung University) ;
- Jang, Mi-Kyung (Department of Food science and Technology, Kyung-Sung University) ;
- Kim, Hae-Sung (Department of Food science and Technology, Kyung-Sung University) ;
- Chung, Soo-Ja (Department of Food and Nutrition, Pusan Woman's Junior College)
- 발행 : 1988.09.01
초록
해수로부터 분리 확인한 비브리오균에서 생산하는 단백 다당체의 항종양 활성에 대하여 조사하였다. 비브리오균을 0.5%-peptone와 0.5% yeast extract가 함유된 해수를 기질로 배양하여 단백 다당체를 얻었다. 단백다당체의 단당류의 함량은 xylose, mannose, galactose, glucose 및 fructose의 순서이고, 주요 아미노산 glutamic acid, serine 및 aspartic acid였다. 단백 다당체의 항종양 활성을 Sarcoma-180에 대하여 0.5mg/kg/day 및 5mg/kg/day을 쥐에 주사했던 바 20.9% 및 43.9%의 억제 효과가 있었다.
The antitumor activity of protein-polysaccharide produced by a strain, Vibrio anguilfarum, No. 17 isolated from sea water was investigated. The extracellular protein,polysaccharide used in this experiment was obtained through the cultivation of Vibrio anguillarum No. 17 at