Synthesis of Poly(hydroxypropyl methacrylate-co-N-vinylpyrrolidone) hydrogel and its Application to the Contact Lens

Poly(hydroxypropyl methacrylate-co-N-vinylpyrrolidone) hydrogel의 합성과 콘텍트렌즈에의 응용

Poly (HPMA/NVP) hydrogel was synthesized according to the composition and the con- centration of the crosslinking agent. The swelling degree of the P(HPMA/NVP) hydrogel decreased with increasing of P(HPMA) composition and crosslinking agent. The glass transi- tion and softening temperatures of the P(HPMA/NVP) increased with increasing of P(HPMA) composition. The composition of P(HPMA/NVP) : 70/30 and the concentration of the crosslin- king agent of 0.5 wt % gave the optimum condition in the application to the contact lens. There were also adequate in the mechanical, refractive properties and in vivo test in the P(HPMA/ NVP): 70/30 system.