Mechanisms of Self-protection and Genes Coding for Antibiotic Biosynthesis, Particularly, in Microorganisms which Produce Antibiotic Inhibitors of Protein Synthesis

항생물질생산균(抗生物質生産菌)의 단백질합성계조해항생물질(蛋白質合性系阻害抗生物質)에 대한 자기내성기구(自己耐性機構)와 생합성유전자(生合成遺傳子)

  • Paik, Soon-Young (Department of Food Technology, College of Agriculture, Korea University) ;
  • Sugiyama, Masanori (Department of Fermentation Technology, Faculty of Engineering, Hiroshima University) ;
  • Yang, Han-Chul (Department of Food Technology, College of Agriculture, Korea University)
  • 백순영 (고려대학교 농과대학 식품공학과) ;
  • 삼산정칙 (광도대학 공학부 발효공학과) ;
  • 양한철 (고려대학교 농과대학 식품공학과)
  • Published : 1988.12.30

Abstract

Streptomycetes are attractive microorganisms for their production of various secondary metabolites such as antibiotics. Now, the development of gene manipulation in this microorganisms enables the cloning and analysis of the genes which coding for antibiotic biosynthesis and resistance to the drug. In this article, we reviewed the studies with respect to the mechanisms of self-protection and cloning of the genes cloning for antibiotic biosynthesis, particularly, in microorganisms which produce antibiotic inhibitors of protein synthesis.

Keywords