YAKHAK HOEJI (약학회지)
- Volume 32 Issue 1
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- Pages.40-49
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- 1988
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
The Effect of 6-Hydroxydopamine on the Anticonvulsant Activity of Clonazepam and Norepinephrine in Brain
뇌내(腦內) Norepinephrine함량변화(含量變化)와 Clonazepam의 항경련효과(抗痙攣效果)에 미치는 6-Hydroxydopamine의 영향(影響)
- Yun, Jae-Soon (College of Pharmacy, Ewha Woman's University) ;
- Kim, Young-Joo (Department of Pharmacy, Seoul National University Hospital)
- Published : 1988.02.29
Abstract
There is evidence that brain norepinephrine may play a role in experimentally induced seizures in animals. Thus the present experiments were undertaken in an attempt to explore the role of brain norepinephrine in anticonvulsant activity of clonazepam. 6-Hydroxydopamine was given to newborn rats and PTZ-induced seizures were tested
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