Journal of agricultural medicine and community health (농촌의학ㆍ지역보건)
- Volume 12 Issue 1
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- Pages.80-93
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- 1987
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- 1738-9577(pISSN)
Studies on the Epidemiological Change of Clonorchiasis After Mass Chemotherapy in Highly endemic Areas
집단치료사업에 따른 간흡충증의 역학적 변동에 관한 조사
- Joo, Kyoung-Hwan (Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University) ;
- Chu, Paul B. (Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University) ;
- Rim, Han-Jong (Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University) ;
- Lee, Joon-Sang (Department of Parasitology and Institute for Tropical Endemic Diseases, College of Medicine, Korea University)
- 주경환 (고려대학교 의과대학 기생충학교실 및 열대풍토병연구소) ;
- 주봉덕 (고려대학교 의과대학 기생충학교실 및 열대풍토병연구소) ;
- 임한종 (고려대학교 의과대학 기생충학교실 및 열대풍토병연구소) ;
- 이준상 (고려대학교 의과대학 기생충학교실 및 열대풍토병연구소)
- Published : 1987.01.01
Abstract
Mass chemotherapy of Clonorchis sinensis infection in Korea was started in 1982 with 40mg/kg body weight single dose administration scheme of praziquantel. The purpose of this study was to investigate the efficiency of current mass chemotherapy project and compare the epidemiological changes in endemic area of Ckmorchis sinensis. This study was performed at Kimhae-city and Samrangjin-eup of Miryang-gun, Kyongnam province, highly endemic area of C. sinensis located southeastern part of Korea from July to October of 1986. The therapy project of Kimhae area was performed in 1984, whereas that of Samrangjin was done in 1985 by stool examination of the Korea Association for Parasite Eradication(KAPE) and drug administration of local health centre. The results obtained were as follows; 1) As a results of stool examination from 234 specimens obtained in Kimhae area, the infection rate has decreased to 34.2%from 45.6p in 1983, but the infection rate of C. sinensis from 341 specimens obtained in Samrangjin area did not decrease (58.1%in 1986 490%in 1983). 2) The study in Kimhae area showed that the average EPG decreased remarkably from 4,858 to 1,340 and those classified above the category of heavy infection decreased also from 14.0pp to 1.7%. The study in Samrangjin area showed that the average EPG did decrease drastically from 9,597 to 6,498 and those classified above the category of heavy infection did not go down drastically from 25.2% to 14.2%. 3) The study in Kimhae area showed decrease of Cs.
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