Toxicological Research
- 제3권1호
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- Pages.15-26
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- 1987
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
MUTAGENIC EVALUATION OF PRANOPROFEN, A NEW ANTI-INFLAMMATORY AGENT
- Moon, Hwa-Hwey (Department of safety Research, National Institute of Helath) ;
- Kim, Pu-Young (Department of safety Research, National Institute of Helath) ;
- Yun, Tai-Bo (Department of safety Research, National Institute of Helath) ;
- Jo, Dae-Hyun (Department of safety Research, National Institute of Helath) ;
- Park, Han-Soo (Department of safety Research, National Institute of Helath) ;
- Heo, Ok-Soon (Department of safety Research, National Institute of Helath) ;
- Kim, Soon-Han (Department of safety Research, National Institute of Helath) ;
- Choi, Suk-Hee (Department of safety Research, National Institute of Helath)
- 발행 : 1987.06.01
초록
The mutagenicity of pranoprofen, a new antiinflammatory agent primarily used in Japan, was evaluated by employing several different methods such as the Ames test, micronucleus test, and the sister chromatid exchange test. For the Ames test, various doses of pranoprofen (5 and 1 mg, 100, 10, and 1
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